ColonSentry Bulletin

Literature

Click here to download the Canadian Journal of Diagnosis - Aug 2009 Issue: ColonSentry: Novel Blood Test Facilitates Detection of Sessile Colon Polyps: A Case Study. (PDF, 502k)

Click here to download the physician English brochure (PDF, 428k)

Click here to download the physician French brochure (PDF, 143k)

Click here to download the simple 3 step process. (PDF, 232k)

Click here to download information about who can benefit from the ColonSentry test. (PDF, 95k)

Click here to download information about interpreting the Current Risk Score. (PDF, 85k)

Click here to download Canadian Journal of Diagnosis Medical Brief: ColonSentry: The World’s First Patient-Friendly Test for Colon Cancer. (PDF, 88k)

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Medical Guidelines

Canadian Sources

• Canadian Association of Gastroenterology (2004)
• Canadian Cancer Society

International Sources

• American Cancer Society (2008)
• Medline
• U.S. National Cancer Institute

Peer-Reviewed Publications

1. Liew CC, Ma J, Tang HC, Zheng R, Dempsey AA.
   Peripheral blood transcriptome dynamically reflects system wide biology: a potential diagnostic tool. Journal of Laboratory and Clinical Medicine. 2006;147:126-32.
   
   

   "...thus hypothesize that blood cells can act as sentinels of disease and that we could capitalize on this property of blood for the diagnosis/prognosis of disease (the “Sentinel Principle”)."
   

   
   
2. Han M, Liew CT, Zhang HW, et al.
   Novel, blood-based five-gene panel biomarker set for the detection of colorectal cancer.  Clinical Cancer Research. 2008;14:455-60.
   
   

   “...applied a unique method to identify genes expressed in whole blood that can serve as biomarkers to detect colorectal cancer (CRC)…"
   

   
   
3. Marshall KW, Chao S, Nossova N, et al.
   Stratification of colorectal cancer probability using six genes from whole blood.  Proceedings of the 99th Annual Meeting of the American Association for Cancer Research; 2008 Apr 12-16; San Diego, CA. Philadelphia (PA): AACR; 2008. Abstract no. LB-214.
   
   

   "Patients can be segregated into Increased Probability, Average Probability and Decreased Probability sub-populations, with an approximate 10-fold difference in probability of having CRC occurring between the Increased and Decreased Probability groups."
   
   

4. Han M, Liew CT, Zhang HW, et al.
   Novel blood biomarker panel detects human colorectal cancer.  ASCO Annual Meeting Proceedings. 2006. Clinical Oncology 2006; Part I. Vol 24 (June 20 Supplement):3611.
   
   

   “...blood biomarker panel was identified with a powerful ability to discriminate CRC from non-CRC samples.”
   

   
   
5. Chin W., and Andrew S.
   The cost-effectiveness of a blood test for colorectal cancer screening. 20th Annual Canadian Agency for Drugs and Technologies in Health (CADTH) Symposium April 5-7, 2009. Ottawa, Ontario.
   For more information: Original Poster (PDF, 60k) and Poster Abstracts (PDF, 718k)
   
   

   “…ColonSentry detected more early stage CRC, saved lives, and lowered the costs associated with late stage CRC.”